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Eden series CHO CD medium

Optimized CD media for high protein production in CHO cell culture

As early as 1998, BioEngine developed China's first serum-free medium for CHO cells. With a deep understanding of the key technologies and parameters of large-scale culture of CHO cells, BioEngine has continuously upgraded and optimized the medium formulation and manufacturing process. Based on rich project experience and an innovative iBioG-Med medium development platform, the first Eden CD CHO medium was launched in 2018 to promote high productivity in large-scale CHO cell culture. So far, Eden CD CHO media have been applied to 60+ clinical projects.

Eden series CHO CD medium

Features

Animal-derived component-free

Protein-free/Peptide ingredients-free

Chemically Defined

DMF Filing in Progress

Universality: Support the culture of various CHO cell lines (CHO-K1, CHO_ZN, Horizon, CHO-S, CHO DG44, etc.) in fed-batch, intensified fed-batch and perfusion modes

Advantages

Equivalent or superior performance to global brand products with better price and lead time;

4 advanced CMPM powder media production lines to meet different customer demand with high inter-batch consistency (CPK*>1.33);

Safe and compliant: chemically defined formulation minimizes the potential of contamination from animal-derived components and meets relevant compliance and regulatory requirements;

EU certified ISO13485:2016 QMS, all data are traceable;

Full documents support for IND application;

Strictly selected the "2 domestic+1 imported" raw material supplier model to to ensure a stable and reliable supply chain;

*CPK is a standard index to state the capability of one process.  CPK=1.33: the process is capable and meets specification limits. The higher the CPK,the better.

Order Information
Basal Medium Feed Medium
Meida KitProductCat. No.SizeFormProduct Instruction (pdf)Inquiries /Sample application
Eden 100 Kit Eden B100S Basal Medium FG0116401 200L Powder    Inquiries /Sample application
FG0116402 10L Powder
Eden F100aS Feed Medium   FG0116501  20L  Powder   
FG0116502  1L Powder
Eden F100bS Feed Medium FGO115601  20L  Powder   
FGO116602  1L  Powder
Eden 601 Kit Eden B601S Basal Medium FG0115601 200L Powder  
FG0115602 100L Powder
FG0115603 10L Powder
Eden F602aS Feed Medium FG0115701 20L Powder
FG0115702 1L Powder
Eden F600bS Feed Medium FG0108801 10L Powder
FG0108802 1L Powder
Tuner ProductCat. No.FormSizePackagingNotesProduct Instruction (pdf)Inquiries /Sample application
Tuner-Sia FG0119101 Powder 100g Bag For modulating sialylation of antibody Inquiries /Sample application
Tuner-Gal FG0119201 Liquid 1L Bottle For modulating galactosylation of antibody
FG0119202 Liquid 100ml Bottle
Tuner-Lac TP0200401 Liquid 200ml Bottle Induce lactate consumption in the later stage of cell cultures  
*DrivingM® is a registered trademark of Shanghai BioEngine Sci-Tech Co., Ltd.
Performance
Antibodies

In fed-batch mode, CHO cells cultured in Eden CD CHO media demonstrate higher viable cell density (VCD) and protein production than global brand A. Antibody titer of different CHO cell lines adapted in Eden CD CHO media reached 2-11 g/L.

 

In pulse perfusion mode, CHO cell cultures in Eden CD CHO media demonstrated superior performance than competitive global brands. When VVD=1.0, volumetric productivity (Vp) can reach up to 2.2 g/L/day, and the cumulative product expression in 14 days can reach 19 g/L, 55% higher than global brand B. When VVD=2.0, Vp can reach up to 3.3g/L/day, and the cumulative product expression in 14 days can reach 25 g/L.

Let us contact you

We have a professional technical team to provide high quality one-stop cell culture service from process development
and optimization, medium formulation design to medium processing and manufacturing for all biopharmaceutical companies.

If you have any question, please click "Quick Message" and leave your message,  we will reply to you as soon as possible.
If anything urgent, please call (86)21-68582660-2792.

BioEngine

3F&4F, Building 3, Lane 396, Lvzhou Ring Road, Minhang District, Shanghai, PRC

(86)21-68582660-2792

globalsales@bio-engine.com.cn

Work hours:9:00-17:00